The Arthritis Foundation is the only national voluntary health organization whose purpose is directed solely to all forms of arthritis. The Arthritis Foundation has national and international programs involving support for scientific research, public information and education for affected patients and their families, training of specialists, public awareness, and local community assistance.

Fever: A mildly elevated temperature is not unusual in a person with active inflammation from rheumatoid arthritis. However, a true fever (temperature is above 100.4 degrees F or 38 degrees C) is not expected and can represent an infection. People with rheumatoid arthritis are at increased risk for infection because of their disease and frequently because of their medications. Many of the medications used to treat rheumatoid disease suppress the immune system of the body that is responsible for defending against infectious microbes. Furthermore, these medications can increase the risk of a more serious infection when a bacterium or virus strikes. It is important for people with rheumatoid arthritis to notify the doctor as soon as a fever occurs so that infections are treated at the earliest time possible. This can minimize the chances for many serious complications of infections.
Cannabis has shown to have positive effects on people suffering from epilepsy and multiple sclerosis. Research conducted in the University College of London, it is also effective in dealing with multiple other neurological conditions like the Dravet syndrome and Parkinson’s disease. It prevents neurodegeneration and cognitive decline, thereby helping those suffering from Alzheimer’s.
Moreover, a patient survey conducted by Project CBD, declared that “…cannabis appears to be an effective pain management tool with few negative side effects.” The study went on to say that a “…significant decrease in opiate usage among elderly patients while taking medical cannabis [was observed during trial].” In short, it has been portrayed clearly numerous times through valid and well-publicized clinical studies that cannabis is a practical option in terms of efficient pain management.
The important thing is that you have to be SUPER careful when selecting CBD oils. Since the cannabis industry is not FDA-regulated, there have been dozens and dozens of companies trying to get away with selling very low quality (and even potentially toxic), “snake oils” that have been extracted using harsh chemical solvents like butane and hexane. Make sure you stay away from cheap products like these, as they could damage your health.
While joint symptoms are considered the primary characteristic of arthritis, certain rheumatic diseases may affect parts of the body other than the joints. For example, connective tissue (found in tendons, muscles, or skin) can be affected. Certain rheumatic conditions may also affect internal organs. The extra-articular manifestations and systemic effects may result in debilitating or even life-threatening complications.
Ive been taking CBD tincture oil for 8 months now. It has made such a positive improvement in my life. I have more energy and I feel better overall. I feel like myself after many years of an overall feeling of lethargy. After taking CBD oil for 6 months, I went to my doctor for a regular check up. All my my bloodwork test results- including A1C and cholesteral- improved. As an added bonus, I lost 25 lbs. All of this without even trying. Adding CBD to my life has given me more energy. I feel like my metabolism has improved. Nowadays, I look forward to each day as what can I do today, while before CBD, my attitude was negative and what do I have to do today. Nothing else in my life has changed. In fact, it has become more stressful due to family illness. But CBD has taken the edge off and continues to be my go-to daily supplement. I use Medterra 500mg tincture oil and take 1/2 a dropper twice a day. Everyone is different, so adjust the amount and strength until you find what works best for you. Definitely do it. Take CBD. Youll be so happy that you did.
Typically, people who experience early signs of arthritis consult with their primary care physician or family physician. That may be appropriate for the first round of diagnostic testing. However, you may be referred to a rheumatologist for more in-depth evaluation and ongoing care. A rheumatologist is a specialist in the diagnosis and treatment of rheumatic diseases.

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Large-scale mutations involve the deletion or gain of a portion of a chromosome. Genomic amplification occurs when a cell gains copies (often 20 or more) of a small chromosomal locus, usually containing one or more oncogenes and adjacent genetic material. Translocation occurs when two separate chromosomal regions become abnormally fused, often at a characteristic location. A well-known example of this is the Philadelphia chromosome, or translocation of chromosomes 9 and 22, which occurs in chronic myelogenous leukemia and results in production of the BCR-abl fusion protein, an oncogenic tyrosine kinase.
The term “marihuana” means all parts of the plant Cannabis sativa L. [sic], whether growing or not; the seeds thereof; the resin extracted from any part of such plant; and every compound, manufacture, salt, derivative, mixture, or preparation of such plant, its seeds or resin. Such term does not include the mature stalks of such plant, fiber produced from such stalks, oil or cake made from the seeds of such plant, any other compound, manufacture, salt, derivative, mixture, or preparation of such mature stalks (except the resin extracted therefrom), fiber, oil or cake, or the sterilized seed of such plant which is incapable of germination.
One idea about why people with cancer are blamed or stigmatized, called the just-world hypothesis, is that blaming cancer on the patient's actions or attitudes allows the blamers to regain a sense of control. This is based upon the blamers' belief that the world is fundamentally just and so any dangerous illness, like cancer, must be a type of punishment for bad choices, because in a just world, bad things would not happen to good people.[199]
In addition, other specialists may be involved depending upon where the cancer is located. For example, ob-gyn specialists may be involved with uterine cancer while an immunologist maybe involved in treatment of cancers that occur in the immune system. Your primary care physician and main oncologist will help you to determine what specialists are best to be members of your treatment team.
In short, the results of the survey (which were published in the Journal of Pain Research) showed that roughly 42% and 46% (respectively) of participants claimed they were able to use cannabis in place of traditional medical to effectively treat their specific medical ailment. So if you’re wondering how to know if you need CBD for pain, remember that you’re certainly not alone.
...with due respect, your experience Locsta is almost precisely what happened with my....chihuahua. Degenerative disc disease, excruciating pain, prednisone worked, but couldn't keep her on it..pain killers and muscle relaxants didn't help, really thought I would have to put her down. Chi bloggers suggested CBD; gave PetReleaf a shot--like you, literally within minutes I could see the difference, in days she was pain free and now is back in charge of our world. The real key here is that with my dog, there is zero, nada, chance that there was any placebo effect...

Kimberly is the reference editor for Live Science and Space.com. She has a bachelor's degree in marine biology from Texas A&M University, a master's degree in biology from Southeastern Louisiana University and a graduate certificate in science communication from the University of California, Santa Cruz. Her favorite stories include animals and obscurities. A Texas native, Kim now lives in a California redwood forest. You can follow her on Twitter @kimdhickok.


Both Bonn-Miller and Ward stress that it's up to the consumer to be well-educated about the material they're purchasing and the research that's out there. "The companies that are creating [cannabis oils] are offering lots of claims about its use that are not necessarily substantiated by any research," Bonn-Miller said. So "I think there needs to be, from a consumer standpoint, a lot of vigilance," he added.
Many people who suffer from arthritis experience either severe chronic pain or moderate chronic pain with occasional episodes of severe pain. Since the degree of pain and disability is highly influenced by an individual's perception of pain and not necessarily correlated with the degree of cartilage degeneration, a treatment plan that includes both conventional and integrative therapies can be very effective. As always, you should make sure that you communicate and share your treatment plan with all of your care providers.
^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.
^ Narayanan L, Fritzell JA, Baker SM, Liskay RM, Glazer PM (April 1997). "Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2". Proceedings of the National Academy of Sciences of the United States of America. 94 (7): 3122–27. Bibcode:1997PNAS...94.3122N. doi:10.1073/pnas.94.7.3122. PMC 20332. PMID 9096356.
Mike, what kind of breast cancer (invasive ductal, I presume)? How many of her lymph nodes were positive? How big was the primary tumor? Reason I ask is that in women with Stage I or IIA tumors that are estrogen-and progesterone-receptor-positive and HER2-negative (ER+/PR+/HER2-) with three or fewer positive lymph nodes, there is a genomic assay test on a sample of the tumor, called OncotypeDX, that will tell doctors whether chemo is necessary or would even work at all. Medicare covers that test 100%.That type of breast cancer mentioned above, which I had as Stage IA, is treated in postmenopausal women with anti-estrogen drugs called aromatase inhibitors(aka AIs: anastrazole, letrozole, or exemestane)which have as a side effect joint pain. CBD oil is effective for this joint pain it is not, I repeat, NOT a substitute for chemo, radiation or these anti-estrogen drugs.So don’t assume your mom’s cancer will require chemo; but if it does, CBD helps with those side effects as well. If she lives in a state where medical marijuana is legal, there are doctors who sub-specialize in certifying applications for a medical marijuana card, and in the interim before the card is issued can advise as to the appropriate dose of CBD oil (legal and over-the-counter in all 50 states). Some (though not most) medical oncologists will certify their own patients’ medical marijuana card applications so she need not seek out another doctor; and will advise the appropriate dose for her symptoms. Once she gets her card, the “budtenders” in the licensed dispensaries can advise her as to the right CBD product (with or without THC), strength, and dosage. If she lives in a state where recreational weed is legal, the “budtenders” in the marijuana shops can steer her to the right strength of CBD oil and the right dosage.
Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.
Millions of people around the world live with diabetes or know someone living with diabetes. Regardless of the type of diabetes, diabetes isn’t yet a curable disease.  However, it is a very treatable disease, and no matter how frightening, annoying, and frustrating it can be, people with diabetes can live long, healthy, and happy lives. Our goal is to provide you the information, tools and resources to help make that happen.
In order to create a system where oils can be provided to patients when the original prescription is expressed in grams of dried product, each Licensed Producer must provide an ‘Equivalency Factor’. This allows you to see how much oil you can purchase to be in line with your prescription and ensures that you do not go over your prescribed allowance. For example, a 60ml bottle of Blueberry Lamsbread Cannabis Oil, which has an equivalency factor of 12 ml of oil to 1 gram of dried cannabis, will use 5 grams of your possession limit.
Heart disease and stroke. People who have diabetes are at greater risk for heart disease and stroke. The risk is even greater for people who have diabetes and smoke, have high blood pressure, have a family history of heart disease, or are overweight. Heart disease is easiest to treat when it is caught early. It is very important to see your doctor on a regular basis. He or she can test for early signs of heart disease. This includes checking cholesterol levels. If your cholesterol is higher than the recommended level, your doctor will talk to you about lifestyle changes and medicine to help get your cholesterol under control.
Hash oil seized in the 1970s had a THC content ranging from 10% to 30%. The oil available on the U.S. West Coast in 1974 averaged about 15% THC.[2] Samples seized across the United States by the Drug Enforcement Administration over an 18-year period (1980–1997) showed that THC content in hashish and hashish oil averaging 12.9% and 17.4%, respectively, did not show an increase over time.[4] The highest THC concentrations measured were 52.9% in hashish and 47.0% in hash oil.[5] Hash oils in use in the 2010s had THC concentrations as high as 90%[6][7] and other products achieving higher concentrations [8]

Pain-relieving creams that are applied to the skin over the joints can provide relief of daytime minor arthritis pain. Examples include capsaicin (ArthriCare, Zostrix, Capsagel), diclofenac cream (Voltaren gel), salicin (Aspercreme), methyl salicylate (Bengay, Icy Hot), and menthol (Flexall). For additional relief of mild symptoms, local ice application can sometimes be helpful, especially toward the end of the day. Occupational therapists can assess daily activities and determine which additional techniques may help patients at work or home.
Cannabis has shown to have positive effects on people suffering from epilepsy and multiple sclerosis. Research conducted in the University College of London, it is also effective in dealing with multiple other neurological conditions like the Dravet syndrome and Parkinson’s disease. It prevents neurodegeneration and cognitive decline, thereby helping those suffering from Alzheimer’s.
Bone erosion is a central feature of rheumatoid arthritis. Bone continuously undergoes remodeling by actions of bone resorbing osteoclasts and bone forming osteoblasts. One of the main triggers of bone erosion in the joints in rheumatoid arthritis is inflammation of the synovium, caused in part by the production of pro-inflammatory cytokines and receptor activator of nuclear factor kappa B ligand (RANKL), a cell surface protein present in Th17 cells and osteoblasts.[32] Osteoclast activity can be directly induced by osteoblasts through the RANK/RANKL mechanism.[33]
^ O'Gara PT, Kushner FG, Ascheim DD, Casey DE, Chung MK, de Lemos JA, Ettinger SM, Fang JC, Fesmire FM, Franklin BA, Granger CB, Krumholz HM, Linderbaum JA, Morrow DA, Newby LK, Ornato JP, Ou N, Radford MJ, Tamis-Holland JE, Tommaso CL, Tracy CM, Woo YJ, Zhao DX, Anderson JL, Jacobs AK, Halperin JL, Albert NM, Brindis RG, Creager MA, DeMets D, Guyton RA, Hochman JS, Kovacs RJ, Kushner FG, Ohman EM, Stevenson WG, Yancy CW (January 2013). "2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines". Circulation. 127 (4): e362–425. doi:10.1161/CIR.0b013e3182742cf6. PMID 23247304.

My dad has severe advanced stage Dementia. Will CBD oil help him at this point? He is now refusing to eat any solid food, but will accept most drinks.In addition, he has lost a great deal of weight even though they're giving him Mega Shakes containing a full meals worth of proteins, etc. He gets at least 4 of these a day..some which he refuses. Is his Dementia too far gone for CBD oils to help him?


Your doctor will test your blood sugar every 3 months with an A1C test. Also, you can test your blood sugar on your own throughout the day. You will need to use a blood glucose monitor to check it on your own. This involves pricking your finger for blood and putting a test strip in the blood to get the results. If your blood sugar gets too low, you might feel tired, experience problems with muscle coordination, sweat, have difficulty thinking or speaking clearly, twitch, feel like you’re going to faint, become pale, lose consciousness, or have a seizure. At the earliest sign of any of these symptoms, eat or drink something that will raise your blood sugar fast. This could include candy, juice, milk, or raisins. If you don’t feel better in 15 minutes or if monitoring shows that your blood sugar level is still too low, eat or drink another item to raise your blood sugar fast. Always keep a supply of these items on hand for emergencies.
I was diagnosed of RHEUMATOID ARTHRITIS (RA) in July 2010, It started in two fingers on my right hand and one finger in my left hand. The right side of my body was constantly aching and fatigue was so severe. I was put on Naproxen and after some time i didn't feel any different,I went on research on the internet and i found several articles of patient that has been healed from ("Hepatitis And ARTHRITIS") with Dr Molemen Natural Medicine,so i started on a natural treatment from DR MOLEMEN HERBAL HEALING MEDICINE, their RA FORMULA Herbal Medicine treatment effectively reversed and healed my Rheumatoid Arthritis condition totally. The swellings,stiffness,fatigue and joint/muscle pains has subsided. I feel better overall. Visit ( drmolemenspiritualtemple @ gmail . com ) or (dr.molemenspiritualtemple @ yahoo . com ) or call him on +2347036013351). Four months after the treatment, I made an appointment with a rheumatologist in Houston, after examining me, she looked at me and told me I did not have Rheumatoid Arthritis. Its almost like a miracle,Thanks for your service Doc!

^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.


Tammy et al, Through trial and error you will find a correct dosage. Try 50 mg daily....25 each 2x daily....if no results up the dosage until it works for you. Remember, there has never been a death from marijuana or CBD use. You might want to try a tincture or rub with CBD and THC. You won't get the psych high from it. Helps my friend with PArkinsons tremors. She takes 50mg of tincture and uses the rub morning and night. It is a miracle for arthritis. Good luck
Diabetes is a disease that occurs when your blood glucose, also called blood sugar, is too high. Blood glucose is your main source of energy and comes from the food you eat. Insulin, a hormone made by the pancreas, helps glucose from food get into your cells to be used for energy. Sometimes your body doesn’t make enough—or any—insulin or doesn’t use insulin well. Glucose then stays in your blood and doesn’t reach your cells.
To be clear, there is no one specific test, scan, or anything else of the sort that you can do to determine whether or not you need CBD oil for pain. Also, since cannabis is not yet recognized by the FDA, you unfortunately can’t really go to your doctor either and have them recommend it; until marijuana is FDA-approved, it cannot be prescribed by physicians.
Numerous diseases — such as anorexia, emesis, pain, inflammation, multiple sclerosis, neurodegenerative disorders, epilepsy, glaucoma, osteoporosis, schizophrenia, cardiovascular disorders, cancer, obesity and metabolic syndrome-related disorders — are being treated or have the potential to be treated by cannabis oils and other cannabinoid compounds.
Methyl Sulfonyl Methane (MSM) has a metabolite that is found naturally in the human body, and is commonly found in green vegetables, garlic, onions, fruits, grains, algae, and milk. It is an important source of sulfur, required for the synthesis of cartilage.  Animal studies suggest MSM decreases inflammatory joint disease, but human studies have not been done. Usual dose is 1000 to 3000 mg three times a day. There may be side effects of nausea, diarrhea, and headaches.

If the amount of insulin available is insufficient, or if cells respond poorly to the effects of insulin (insulin insensitivity or insulin resistance), or if the insulin itself is defective, then glucose is not absorbed properly by the body cells that require it, and is not stored appropriately in the liver and muscles. The net effect is persistently high levels of blood glucose, poor protein synthesis, and other metabolic derangements, such as acidosis.[59]
To treat diabetic retinopathy, a laser is used to destroy and prevent the recurrence of the development of these small aneurysms and brittle blood vessels. Approximately 50% of patients with diabetes will develop some degree of diabetic retinopathy after 10 years of diabetes, and 80% retinopathy after 15 years of the disease. Poor control of blood sugar and blood pressure further aggravates eye disease in diabetes.
Of course, though, they offer less potent oils than that, with a product lineup that ranges from 300 mg CBD per bottle to 4,000 mg. Naturally the 4,000 mg option is the most expensive (this is the one that provides the “bomb” 60 mg dose), as it currently sells for $299. For long-term pain and anxiety relief, though, it may be well worth it if it is effective for you and helps replace your regular meds.
Creatinine is a chemical waste molecule that is generated from muscle metabolism. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles. Creatinine has been found to be a fairly reliable indicator of kidney function. As the kidneys become impaired the creatinine level in the blood will rise. Normal levels of creatinine in the blood vary from gender and age of the individual.

Deaths from cancer were 5.8 million in 1990.[171] Deaths have been increasing primarily due to longer lifespans and lifestyle changes in the developing world.[22] The most significant risk factor for developing cancer is age.[172] Although it is possible for cancer to strike at any age, most patients with invasive cancer are over 65.[172] According to cancer researcher Robert A. Weinberg, "If we lived long enough, sooner or later we all would get cancer."[173] Some of the association between aging and cancer is attributed to immunosenescence,[174] errors accumulated in DNA over a lifetime[175] and age-related changes in the endocrine system.[176] Aging's effect on cancer is complicated by factors such as DNA damage and inflammation promoting it and factors such as vascular aging and endocrine changes inhibiting it.[177]
Maturity onset diabetes of the young (MODY) is a rare autosomal dominant inherited form of diabetes, due to one of several single-gene mutations causing defects in insulin production.[51] It is significantly less common than the three main types. The name of this disease refers to early hypotheses as to its nature. Being due to a defective gene, this disease varies in age at presentation and in severity according to the specific gene defect; thus there are at least 13 subtypes of MODY. People with MODY often can control it without using insulin.
My husband has RSD and we are considering CBD oil -= I would ask at Hempmed because the spray won't have enough in it. Our dgt';s friend has ovarian cancer and it is shrinking her tumors but the spray would never have been enough. I would get CBD oil and check with Hempmeds to see what they suggest. It isn't cheap but it does work. LOW dose Naltrexone about 4.5 mg is very helpful for RSD and is usually used for getting people off of drugs but is working on turning off the glial cells that surround the nerve that is causing the nerve to scream in pain. We are also using PeaPure that is out of the Netherlands and we are seeing a response, even though small. His other leg touched the painful leg without causing more severe pain. That is progress. We also are using Poison Ivy Cream through Meadowlake Farms that has helped the burning surface pain. Change your diet and get rid of Gluten and Sugar, anything that causes inflammation. This is to allow your own body to work. Absolutely do not use any pain killers as it will turn up your pain. all the Hydrocodone, etc causes neural inflammation and so it will keep cascading higher your pain. Hope this is helpful. Mary
The three most common childhood cancers are leukemia (34%), brain tumors (23%) and lymphomas (12%).[180] In the United States cancer affects about 1 in 285 children.[181] Rates of childhood cancer increased by 0.6% per year between 1975 and 2002 in the United States[182] and by 1.1% per year between 1978 and 1997 in Europe.[180] Death from childhood cancer decreased by half between 1975 and 2010 in the United States.[181]
People with hand arthritis can have trouble with simple activities of daily living tasks (ADLs), such as turning a key in a lock or opening jars, as these activities can be cumbersome and painful. There are adaptive aids or (assistive devices (ADs)) available to help with these tasks,[48] but they are generally more costly than conventional products with the same function. It is now possible to 3-D print adaptive aids, which have been released as open source hardware to reduce patient costs.[49][50] Adaptive aids can significantly help arthritis patients and the vast majority of those with arthritis need and use them.[51]

Targeted therapy is a form of chemotherapy that targets specific molecular differences between cancer and normal cells. The first targeted therapies blocked the estrogen receptor molecule, inhibiting the growth of breast cancer. Another common example is the class of Bcr-Abl inhibitors, which are used to treat chronic myelogenous leukemia (CML).[4] Currently, targeted therapies exist for many of the most common cancer types, including bladder cancer, breast cancer, colorectal cancer, kidney cancer, leukemia, liver cancer, lung cancer, lymphoma, pancreatic cancer, prostate cancer, skin cancer, and thyroid cancer as well as other cancer types.[145]


Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.

Symptoms of fibromyalgia include chronic musculoskeletal pain. The use of cannabis oil for pain can also be a part of natural fibromyalgia treatment. A 2018 study published in the Journal of Clinical Rheumatology looked at the effects of medical cannabis on 26 fibromyalgia patients. The researchers found that after an average of about 11 months of medical cannabis use, all of the patients reported a significant improvement in every parameter on the questionnaire, and 13 patients (50 percent) stopped taking any other medications for fibromyalgia.
Numbness or tingling: When a joint swells, it can pinch the nerves of sensation that pass next to it. If the swelling irritates the nerve, either because of the inflammation or simply because of pressure, the nerve can send sensations of pain, numbness, and/or tingling to the brain. This is called nerve entrapment. Nerve entrapment most frequently occurs at the wrist (carpal tunnel syndrome) and elbow (ulnar nerve entrapment). It is important to have nerve entrapment treated early for best results. A rare form of nerve disease in patients with rheumatoid arthritis that causes numbness and/or tingling is neuropathy. Neuropathy is nerve damage that in people with rheumatoid arthritis can result from inflammation of blood vessels (vasculitis). Vasculitis is not common, but it is very dangerous. Therefore, it is important to notify the doctor if numbness and/or tingling occurs.
The side effects and risks involved with consuming marijuana-based products aren't clear, either, Bonn-Miller said. It's important to "determine cannabinoids that are useful therapeutically while understanding and using cannabinoids that are associated with less risk," he said. At least with CBD, he said, it doesn't appear to have the potential for addiction. That's different from THC, which has been associated with addiction, he said, and negative side effects, including acute anxiety.
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