Replication of the data contained within the DNA of living cells will probabilistically result in some errors (mutations). Complex error correction and prevention is built into the process and safeguards the cell against cancer. If a significant error occurs, the damaged cell can self-destruct through programmed cell death, termed apoptosis. If the error control processes fail, then the mutations will survive and be passed along to daughter cells.
Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain.[30] It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12.[12] Although currently classified as orphan receptors, these receptors are most closely related phylogenetically to the cannabinoid receptors.[12] In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist,[31] and this action may be involved in its antidepressant,[32][33] anxiolytic,[33][34] and neuroprotective effects.[35][36] It is an allosteric modulator of the μ- and δ-opioid receptors as well.[37] The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.[7]
There are many things that can be done to preserve joint function, mobility and quality of life. Learning about the disease and treatment options, making time for physical activity and maintaining a healthy weight are essential. Arthritis is a commonly misunderstood disease. The Arthritis Foundation is the only nonprofit organization dedicated to serving all people with arthritis. Its website, arthritis.org, has many resources for learning about arthritis, practical tips for daily living and more.
Abnormal cholesterol and triglyceride levels. If you have low levels of high-density lipoprotein (HDL), or "good," cholesterol, your risk of type 2 diabetes is higher. Triglycerides are another type of fat carried in the blood. People with high levels of triglycerides have an increased risk of type 2 diabetes. Your doctor can let you know what your cholesterol and triglyceride levels are.
Well, at some point you’ve really just got to rely on word of mouth from folks who have bought hemp oil online from multiple different brands, and can accurately compare one against the other. As you’ll see, PureKana is just one of a small handful that consistently pops up on unbiased, third-party websites as being one of the most potent, pure, and effect CBD oils on the market.
The incidence of cancer and cancer types are influenced by many factors such as age, gender, race, local environmental factors, diet, and genetics. Consequently, the incidence of cancer and cancer types vary depending on these variable factors. For example, the World Health Organization (WHO) provides the following general information about cancer worldwide:

Septic arthritis is an infection of the joint. Most often bacteria reach the joint through the bloodstream from an infection in another part of the body, such as the urinary tract. Infected joints are typically warm, red, and acutely tender. They are often swollen due to pus in the joint. An infected joint often needs surgical drainage in addition to antibiotics.
^ Rutjes, Anne Ws; Nüesch, Eveline; Sterchi, Rebekka; Kalichman, Leonid; Hendriks, Erik; Osiri, Manathip; Brosseau, Lucie; Reichenbach, Stephan; Jüni, Peter (2009-10-07). "Transcutaneous electrostimulation for osteoarthritis of the knee" (PDF). The Cochrane Database of Systematic Reviews (4): CD002823. doi:10.1002/14651858.CD002823.pub2. ISSN 1469-493X. PMID 19821296.
The oil may be further refined by 1) alkali washing, or removing the heavy aromatic carboxylic acids with antibiotic properties, which may cause heartburn, gallbladder and pancreas irritation, and resistance to hemp antibiotics; 2) conversion of CBD to THC. Process 1) consists of dissolving the oil in a nonpolar solvent such as petroleum ether, repeatedly washing (saponifying) with a base such as sodium carbonate solution until the yellow residue disappears from the watery phase, decanting, and washing with water to remove the base and the saponified components (and evaporating the solvents). This process reduces the oil yield, but the resulting oil is less acidic, easier digestible and much more potent (almost pure THC). Process 2) consists of dissolving the oil in a suitable solvent such as absolute ethanol containing 0.05% hydrochloric acid, and boiling the mixture for 2 hours.[17]
Diagnosing a new cancer in a pregnant woman is difficult, in part because any symptoms are commonly assumed to be a normal discomfort associated with pregnancy. As a result, cancer is typically discovered at a somewhat later stage than average. Some imaging procedures, such as MRIs (magnetic resonance imaging), CT scans, ultrasounds and mammograms with fetal shielding are considered safe during pregnancy; some others, such as PET scans, are not.[219]
DM occurs when the body cannot produce enough insulin or cannot respond appropriately to insulin. Insulin is a hormone that the body needs to absorb and use glucose (sugar) as fuel for the body’s cells. Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications.
Systemic lupus erythematosus (SLE) is an autoimmune disease that can involve the skin, kidneys, blood vessels, joints, nervous system, heart, other internal organs. Symptoms vary, but may include skin rash, arthritis, fever, anemia, fatigue, hair loss, mouth ulcers, and kidney problems. Symptoms usually appear in women of childbearing age, but can occur in children or older people. About 90 percent of people affected are women.
It is well known that people who consume cannabis in other forms notice increased appetite, famously called “the munchies”. However, cannabis essential oil can help regulate your appetite and induce hunger, while also stimulating your digestive system to operate at a regular level. This can help people who want to gain weight quickly, particularly after an extended illness or injury.
A 2013 case report conducted in Canada evaluated the beneficial effects of cannabis oil on a 14-year-old female patient diagnosed with acute lymphoblastic leukemia, also known as ALL. For this particular patient, a standard bone marrow transplant, aggressive chemotherapy and radiation therapy were revoked, with treatment being deemed a failure after 34 months. She was extremely ill and severely underweight at this time.
Medterra is the only CBD brand I order from. I was a little skeptical about CBD at first but tried it on the advice of my doctor. I suffer from chronic pain and the only thing that helps the pain is this oil. It really helps with my back pain and I use the tincture and the new Cooling Cream. And the best part is that there are no side effects I dont feel drowsy or unfocused and it doesnt interact with other medications. And Medterra is a fantastic company. One time the shipping of my oil was delayed for some reason and they sent it using express shipping without an added cost Their service is great.

Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.
When you eat, your body changes most of the food you digest into glucose (a form of sugar). A hormone called insulin allows this glucose to enter all the cells of your body. There it is used for energy. Insulin is produced by the pancreas. In someone who has type 2 diabetes, the pancreas doesn’t make enough insulin or the body’s cells can’t use insulin properly (called insulin resistance). This causes glucose to build up in your blood instead of moving into the cells. Too much glucose in the blood can lead to serious health problems that damage the blood vessels, nerves, heart, eyes, and kidneys.
In patients with type 2 diabetes, stress, infection, and medications (such as corticosteroids) can also lead to severely elevated blood sugar levels. Accompanied by dehydration, severe blood sugar elevation in patients with type 2 diabetes can lead to an increase in blood osmolality (hyperosmolar state). This condition can worsen and lead to coma (hyperosmolar coma). A hyperosmolar coma usually occurs in elderly patients with type 2 diabetes. Like diabetic ketoacidosis, a hyperosmolar coma is a medical emergency. Immediate treatment with intravenous fluid and insulin is important in reversing the hyperosmolar state. Unlike patients with type 1 diabetes, patients with type 2 diabetes do not generally develop ketoacidosis solely on the basis of their diabetes. Since in general, type 2 diabetes occurs in an older population, concomitant medical conditions are more likely to be present, and these patients may actually be sicker overall. The complication and death rates from hyperosmolar coma is thus higher than in diabetic ketoacidosis.
Regular dental visits are important. Research suggests that treating gum disease can help improve blood sugar control in patients living with diabetes, decreasing the progression of the disease. Practicing good oral hygiene and having professional deep cleanings done by your dentist can help to lower your HbA1c. (This is a lab test that shows your average level of blood sugar over the previous three months. It indicates how well you are controlling your diabetes.)
Large-scale mutations involve the deletion or gain of a portion of a chromosome. Genomic amplification occurs when a cell gains copies (often 20 or more) of a small chromosomal locus, usually containing one or more oncogenes and adjacent genetic material. Translocation occurs when two separate chromosomal regions become abnormally fused, often at a characteristic location. A well-known example of this is the Philadelphia chromosome, or translocation of chromosomes 9 and 22, which occurs in chronic myelogenous leukemia and results in production of the BCR-abl fusion protein, an oncogenic tyrosine kinase.
CBD (Cannabidiol) is a potent, non-psychoactive cannabinoid found in hemp oil. It is typically extracted from industrial hemp plants that are naturally high in CBD and other phytochemicals. It is the most prevalent of over 80 different cannabinoids found in natural hemp. It is commonly used for its therapeutic properties. Cannabidiol is responsible for a wide-range of positive health benefits through its interaction with the body's own endocannabinoid system.
These diabetes complications are related to blood vessel diseases and are generally classified into small vessel disease, such as those involving the eyes, kidneys and nerves (microvascular disease), and large vessel disease involving the heart and blood vessels (macrovascular disease). Diabetes accelerates hardening of the arteries (atherosclerosis) of the larger blood vessels, leading to coronary heart disease (angina or heart attack), strokes, and pain in the lower extremities because of lack of blood supply (claudication).
S-Adenylmethionine (SAMe) is another naturally occurring molecule in the body, and has been found to stimulate cartilage growth and repair. A deficiency of SAMe in the joint may contribute to cartilage degeneration.  It has been compared to ibuprofen, and found to be as effective and better tolerated.  Dosage range is 400 to 1600 mg daily in divided doses; with 600 mg twice a day being most common. SAMe works slower than NSAIDs and should be tried for at least 4 weeks.
My mom is late stage dementia. We have tried coconut oil/black pepper/curcumin combo for years. Gives only tine bit of help, and is not something that reverses dementia. Maybe in someone who can score better than a 14 on the mme it could be of help. But cannabinoid is a different story. Cannabinoids produce better results in less time. Can't say yet that they will reverse anything though.

This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.


Some studies, but not all, have suggested that the food supplements glucosamine and chondroitin can relieve symptoms of pain and stiffness for some people with osteoarthritis. These supplements are available in pharmacies and health-food stores without a prescription, although there is no certainty about the purity of the products or the dose of the active ingredients because they are not monitored by the FDA. The U.S. National Institutes of Health (NIH) is studying glucosamine and chondroitin in the treatment of osteoarthritis. Their initial research demonstrated only a minor benefit in relieving pain for those with the most severe osteoarthritis. Further studies, it is hoped, will clarify many issues regarding dosing, safety, and effectiveness of these products for osteoarthritis. Patients taking blood-thinners should be careful taking chondroitin as it can increase the blood-thinning effect and cause excessive bleeding. Fish oil supplements have been shown to have some anti-inflammation properties, and increasing the dietary fish intake and/or taking fish oil capsules (omega-3 capsules) can sometimes reduce the inflammation of arthritis.

In a small study published in the journal JCI Insight in 2017, researchers observed that CBD may help prevent stress-related changes in blood pressure. For the study, nine healthy male volunteers took a single dose of either CBD or placebo. Compared to those given the placebo, those treated with CBD had lower blood pressure both before and after experiencing a stressful event.

Bought this for my wife who suffers from chronic pain in her back and hip. She has taken a fairly low dose of Tramadol for the last four years At her worst 3-50mg pills a day. She wanted to reduce the use of the Tramadol because of the addictive properties and started to wean herself down taking half doses approximately three months ago. After some substantial research I bought her a bottle of Medterra because of the consistent positive reviews. She has literally tried almost any and every Dr recommended course of action including Graston technique spinal injections needling physical therapy etc. Started off with a bottle of 500 mg twice a day with minimal results. She started using the 1000 mg bottle twice a day a few weeks ago. While on vacation last week she stopped taking Tramadol all together and as of today is nine days free from taking her prescription. She still has minor withdraw symptoms but is dealing with them in hopes they subside quickly. Bottom line to her this product is working and she is VERY VERY happy to be free from prescription narcotics. This product is more expensive than her Tramadol but I am happy to pay the difference for her peace of mind. In closing I wanted to add I have contacted Medterra a handful of times while doing research and also for customer service questions. They are consistently courteous knowledgeable friendly.

Hi, I work in a communication company I want to share my testimony to the world, my name is Morgan Mary , i am from united kingdom in Belfast north Ireland, I was a stripper in a club I got effected with HIV due to the nature of my job, In April 15 2013 i was tested positive to HIV, This is not design to convince you but its just a personal health experience . I never taught doctor NATHAN could ever get my HIV-AIDS cured with his healing herb spell, i have tried almost everything but I couldn’t find any solution on my disease, despite all these happening to me, i always spend a lot to buy a HIV drugs from hospital and taking some several medications but no relieve, until one day i was just browsing on the internet when i came across a great post of !Michelle! who truly said that she was been diagnose with HIV and was healed that very week through the help of this great powerful healing spell doctor ,I wonder why he is called the great papa NATHAN, i never knew it was all because of the great and perfect work that he has been doing that is causing all this. so I quickly contacted him, and he ask me some few questions and so i did all the things he asked me to do,He ask me to buy some herbs and which I did for my cure,only to see that at the very day which he said i will be healed, all the strength that has left me before rush back and i becomes very strong and healthy, this disease almost kills my life all because of me, so i went to hospital to give the final test to the disease and the doctor said i am HIV negative, i am very amazed and happy about the healing doctor NATHAN gave to me from the ancient part of Africa, you can email him now for your own healing too on his email dromoyespellcastertemple@outlook.com or call +2347036484707
^ Rutjes, Anne Ws; Nüesch, Eveline; Sterchi, Rebekka; Kalichman, Leonid; Hendriks, Erik; Osiri, Manathip; Brosseau, Lucie; Reichenbach, Stephan; Jüni, Peter (2009-10-07). "Transcutaneous electrostimulation for osteoarthritis of the knee" (PDF). The Cochrane Database of Systematic Reviews (4): CD002823. doi:10.1002/14651858.CD002823.pub2. ISSN 1469-493X. PMID 19821296.

In 1937, the U.S. Treasury Department introduced the Marihuana Tax Act, which imposed a levy of $1 per ounce for medicinal use of cannabis and $100 per ounce for recreational use. This was opposed by physicians who were not required to pay a special tax for prescribing cannabis, use special order forms to obtain it and keep records detailing its professional use. The American Medical Association believed that evidence of cannabis’ harmful effects was limited and the act would prevent further research into its medicinal worth.

exhaustion and pain that kept her on the couch much of the day. The 58-year-old Seattle speech coach didn’t want to take opioid pain-killers, but Tylenol wasn’t helping enough. Roth was intrigued when women in her online chat group enthused about a cannabis-derived oil called cannabidiol (CBD) that they said relieved pain without making them high. So Roth, who hadn’t smoked weed since college but lived in a state where cannabis was legal, walked into a dispensary and bought a CBD tincture. “Within a few hours of placing the drops in my mouth, the malaise and achiness that had plagued me for weeks lifted and became much more manageable,” she says. She took the drops several times a day and in a few weeks was back to her regular life.

These cannabinoid-rich extracts can pose risks to patients who consume them. The exact composition of different available oils is frequently unknown. They are not checked for quality by external certified laboratories for the presence of residual solvents, or contaminants such as microbes, pesticides, heavy metals or mycotoxins. The lack of standardisation of both the cannabis starting material and oils makes it impossible to fully evaluate their therapeutic effects over time and, hence, their medicinal value.

^ Jump up to: a b c d Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389. PMC 3481531. PMID 23108553.


Its a pleasure for me to write this testimony about how i got my Genital Herpes cured a month ago. i have been reading so many comments of some people who were cured from various diseases by Dr .Obor but i never believed them. I was hurt and depressed so I was too curious and wanted to try Dr. Obor, then i contacted him through his email when i contact him, he assured me 100% that he will heal me, i pleaded with him to help me out. My treatment was a great success, he healed me just as he promised. he sent me his medication and ask me to go for check up after one weeks of taking the medication. i agreed with him i took this medication and went for check up a , to my greatest surprise my result was negative after the treatment, i am really happy that i am cured and healthy again. I have waited for 3 weeks to be very sure i was completely healed before writing this testimony. I did another blood test one week ago and it was still Herpes negative. so i guess its time i recommend anyone going through Herpes HSV-1 or HSV-2, HIV, HPV, Hepatitis B, Diabetes, Cancer reach him through Email OR add on whatsapp +2348105813057

I placed my first order well over a month ago, but wanted to wait until I could give a more accurate review of Medterras CBD tincture. Ive dealt with the pain of fibromyalgia for many years, and never wanted to take the harsh prescription drugs usually associated with the condition (the side effects seem worse than living with the condition itself!). I did a great deal of research on hemp CBD and thought Id at least give it a try. I am both surprised and pleased to report that I have found a significant difference since taking CBD. Obviously, I cant say that it will work for everyone and every condition, but I will say that at least in my case, it has improved the quality of my body movement significantly. Certainly worth a try if you are at all hesitant.


During the holidays last?year, Nancy and Brent Berry of Danbury, Iowa, went on a train ride with their children and grandchildren, after a?two-hour car ride to get there. They?ve been horseback riding with friends. They?re laughing, running errands together, and hosting their grandchildren for overnight stays. Not long?ago, they couldn't enjoy any of those activities. [...]
Diabetic nephropathy (kidney damage). This is damage to the blood vessels in your kidneys. This means your kidneys have trouble filtering out waste. Some people who have nephropathy will eventually need dialysis (a machine treatment that eliminates waste from the blood) or a kidney transplant. The risk for nephropathy is increased if you have both diabetes and high blood pressure, so it is important to control both of these conditions. Protein in the urine is usually the first sign of nephropathy. This should be checked yearly.

Gout is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gouty arthritis caused by the formation of rhomboid crystals of calcium pyrophosphate known as pseudogout. In the early stages, the gouty arthritis usually occurs in one joint, but with time, it can occur in many joints and be quite crippling. The joints in gout can often become swollen and lose function. Gouty arthritis can become particularly painful and potentially debilitating when gout cannot successfully be treated.[35] When uric acid levels and gout symptoms cannot be controlled with standard gout medicines that decrease the production of uric acid (e.g., allopurinol, febuxostat) or increase uric acid elimination from the body through the kidneys (e.g., probenecid), this can be referred to as refractory chronic gout or RCG.[36]
People with hand arthritis can have trouble with simple activities of daily living tasks (ADLs), such as turning a key in a lock or opening jars, as these activities can be cumbersome and painful. There are adaptive aids or (assistive devices (ADs)) available to help with these tasks,[48] but they are generally more costly than conventional products with the same function. It is now possible to 3-D print adaptive aids, which have been released as open source hardware to reduce patient costs.[49][50] Adaptive aids can significantly help arthritis patients and the vast majority of those with arthritis need and use them.[51]
So totally blown away by Medterra CBD oil. I have taken other brands and nothing compares to Medterra. I like that it is certified THC free and grown and manufactured right here in the U.S. The shipping was very reasonable and I received my oil within about 4-5 days. They also offer a 30 day money back guarantee if I decide to return. ( but I won’t!!!). You can’t go wrong with Medterra for your joint and body aches. I’m finally able to sleep at night again!! Thank you Medterra !!!!
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Cross-sectional studies have found a direct correlation between more severe PTSD symptomatology and increased motivation to use cannabis for coping purposes, especially among patients with difficulties in emotional regulation or stress tolerance. When using cannabis treatment, military veterans with PTSD reported reduced anxiety and insomnia and improved coping ability. (5)


Systemic lupus erythematosus (SLE) is an autoimmune disease that can involve the skin, kidneys, blood vessels, joints, nervous system, heart, other internal organs. Symptoms vary, but may include skin rash, arthritis, fever, anemia, fatigue, hair loss, mouth ulcers, and kidney problems. Symptoms usually appear in women of childbearing age, but can occur in children or older people. About 90 percent of people affected are women.
The important thing is that you have to be SUPER careful when selecting CBD oils. Since the cannabis industry is not FDA-regulated, there have been dozens and dozens of companies trying to get away with selling very low quality (and even potentially toxic), “snake oils” that have been extracted using harsh chemical solvents like butane and hexane. Make sure you stay away from cheap products like these, as they could damage your health.
"Total joint replacement" is a surgical procedure whereby a destroyed joint is replaced with artificial materials. For example, the small joints of the hand can be replaced with plastic material. Large joints, such as the hips or knees, are replaced with metals. Total hip and total knee replacements are now commonplace. These can bring dramatic pain relief and improved function.
Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
God bless Dr Osalu for his marvelous work in my life, I was diagnosed of HERPES SIMPLEX VIRUS since 2010 and I was taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr Osalu, how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine within 3days. I took the medicine as prescribed by him and 2weeks later i was cured from HERPES contact him via email drosaluherbalhome @ gmail . com once again thanks to you Dr Osalu. cure the flowing virus, contact his email or add him on whatsapp +2348078668950

Systemic lupus erythematosus (SLE) is an autoimmune disease that can involve the skin, kidneys, blood vessels, joints, nervous system, heart, other internal organs. Symptoms vary, but may include skin rash, arthritis, fever, anemia, fatigue, hair loss, mouth ulcers, and kidney problems. Symptoms usually appear in women of childbearing age, but can occur in children or older people. About 90 percent of people affected are women.


Insulin is a hormone that is produced by specialized cells (beta cells) of the pancreas. (The pancreas is a deep-seated organ in the abdomen located behind the stomach.) In addition to helping glucose enter the cells, insulin is also important in tightly regulating the level of glucose in the blood. After a meal, the blood glucose level rises. In response to the increased glucose level, the pancreas normally releases more insulin into the bloodstream to help glucose enter the cells and lower blood glucose levels after a meal. When the blood glucose levels are lowered, the insulin release from the pancreas is turned down. It is important to note that even in the fasting state there is a low steady release of insulin than fluctuates a bit and helps to maintain a steady blood sugar level during fasting. In normal individuals, such a regulatory system helps to keep blood glucose levels in a tightly controlled range. As outlined above, in patients with diabetes, the insulin is either absent, relatively insufficient for the body's needs, or not used properly by the body. All of these factors cause elevated levels of blood glucose (hyperglycemia).
These cannabinoid-rich extracts can pose risks to patients who consume them. The exact composition of different available oils is frequently unknown. They are not checked for quality by external certified laboratories for the presence of residual solvents, or contaminants such as microbes, pesticides, heavy metals or mycotoxins. The lack of standardisation of both the cannabis starting material and oils makes it impossible to fully evaluate their therapeutic effects over time and, hence, their medicinal value.
Numerous diseases — such as anorexia, emesis, pain, inflammation, multiple sclerosis, neurodegenerative disorders, epilepsy, glaucoma, osteoporosis, schizophrenia, cardiovascular disorders, cancer, obesity and metabolic syndrome-related disorders — are being treated or have the potential to be treated by cannabis oils and other cannabinoid compounds.
Zuardi, A. W., Crippa, J. A., Hallak, J. E., Bhattacharyya, S., Atakan, Z., Martin-Santos, R., … & Guimarães, F. S. (2012). A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation [Abstract]. Current Pharmaceutical Design, 18(32), 5,131–5,140. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22716160

In several US survey studies, many older patients with arthritis reported using complementary and alternative treatments. The most commonly used treatments were massage therapy (57%) and chiropractic (21%). The use of complementary therapies for arthritis was most common among those who considered themselves in poorer health and who also used traditional healthcare resources more.
Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.

One study of over 100 patients with osteoarthritis in the hip compared a five-week manual therapy program, including manipulations and joint mobilization, to an exercise program. Eighty-one percent of individuals had general perceived improvement after manual therapies, while only 50% experienced that in the exercise group. Patients in the manual therapy group had significantly better outcomes on pain, stiffness, hip function, and range of motion. These improvements lasted through at least 29 weeks. 
The patient continued to use cannabis oil for 65 days. The family changed strains of the oil repeatedly, and some were more effective in increasing appetite and alleviating pain than others. The author of the case report suggests that cannabis oil needs to be explored further because there is potential that cannabinoids might show selectivity when attacking cancer cells, thereby reducing the widespread cytotoxic effects of conventional chemotherapeutic agents. Sadly, the young girl with ALL passed away due to gastrointestinal bleeding and a bowel perforation.
In patients with type 2 diabetes, stress, infection, and medications (such as corticosteroids) can also lead to severely elevated blood sugar levels. Accompanied by dehydration, severe blood sugar elevation in patients with type 2 diabetes can lead to an increase in blood osmolality (hyperosmolar state). This condition can worsen and lead to coma (hyperosmolar coma). A hyperosmolar coma usually occurs in elderly patients with type 2 diabetes. Like diabetic ketoacidosis, a hyperosmolar coma is a medical emergency. Immediate treatment with intravenous fluid and insulin is important in reversing the hyperosmolar state. Unlike patients with type 1 diabetes, patients with type 2 diabetes do not generally develop ketoacidosis solely on the basis of their diabetes. Since in general, type 2 diabetes occurs in an older population, concomitant medical conditions are more likely to be present, and these patients may actually be sicker overall. The complication and death rates from hyperosmolar coma is thus higher than in diabetic ketoacidosis.
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CBD oil is often a co-product or byproduct of industrial hemp grown primarily for another purpose. Farmers can make additional money if they sell their unused hemp biomass to a business that wants to extract CBD from the leftovers. This dual-use practice is widespread and barely regulated, if at all, and the hemp biomass is often tainted with residues of pesticides and toxic solvents that are used to extract the CBD.
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