Some cases of diabetes are caused by the body's tissue receptors not responding to insulin (even when insulin levels are normal, which is what separates it from type 2 diabetes); this form is very uncommon. Genetic mutations (autosomal or mitochondrial) can lead to defects in beta cell function. Abnormal insulin action may also have been genetically determined in some cases. Any disease that causes extensive damage to the pancreas may lead to diabetes (for example, chronic pancreatitis and cystic fibrosis). Diseases associated with excessive secretion of insulin-antagonistic hormones can cause diabetes (which is typically resolved once the hormone excess is removed). Many drugs impair insulin secretion and some toxins damage pancreatic beta cells. The ICD-10 (1992) diagnostic entity, malnutrition-related diabetes mellitus (MRDM or MMDM, ICD-10 code E12), was deprecated by the World Health Organization (WHO) when the current taxonomy was introduced in 1999.[52]
The arthritis journey will surely test your patience. Arthritis, depending on the severity, can be very intrusive. It can be life-changing. It can stir negative emotions within you. You must always fight back. Fight to maintain the highest quality of life possible. Fight to stay positive. Fight to accept the things that have changed because of arthritis. At Verywell, we will provide you with information to help ensure your fight is a healthy one.

100% organic quality is all we deal. Only select, organic growers and extraction processes are used in any product found here. Our pure CBD oil products and tinctures get to work quickly through direct, oral administration. As a capsular, daily supplement, we also have some of the best in quality CBD supplements for the easy, daily maintenance option. For those that prefer vaping, we are also proud to feature an entire line of 100% organic CBD oil vaping products including dab oils, vape oils, and even high quality vape kits.


CBD oil or Cannabis is recommended for people dealing with chronic pain. This oil is said to reduce inflammation, pain and overall discomfort associated with various health conditions. This oil is extracted from cannabis, which is a type of cannabinoid. It is a chemical which is found naturally in hemp plants and marijuana. The application of CBD oil can provide great relief from severe pain in the body.
Better methods are becoming available to more accurately define which patients are more likely to develop more aggressive disease. Gene profiling, also known as gene array analysis, is being identified as a helpful method of defining which people will respond to which medications. Studies are underway that are using gene array analysis methods to determine which patients will be at more risk for more aggressive disease. Finally, genetic research and engineering is likely to bring forth many new avenues for earlier diagnosis and accurate treatment in the near future. This is all occurring because of technology improvements. We are at the threshold of tremendous improvements in the way rheumatoid arthritis is managed.

There is no scientific evidence or research on CBD as an effective treatment for migraine—in large part because it has not been formally studied. However, it may still be a viable topical option for some patients with joint and muscle pain associated with migraine. “If you have a lot of neck pain or soreness, it is perfectly reasonable to use CBD oil. It may even prevent nausea and vomiting,” Dr. Silberstein says.
As with a fermented food like kombucha, slight natural variations are normal and to be expected in a product such as CBD oil because it is made from living plants. Changes in the weather, soil, and water can all impact the biology of the source material. While we verify Certificates of Analysis (and take many other criteria into consideration during our review process), even the most reputable five-star companies have no way to control for every variable in this organic process.
Cataracts and glaucoma are also more common among diabetics. It is also important to note that since the lens of the eye lets water through, if blood sugar concentrations vary a lot, the lens of the eye will shrink and swell with fluid accordingly. As a result, blurry vision is very common in poorly controlled diabetes. Patients are usually discouraged from getting a new eyeglass prescription until their blood sugar is controlled. This allows for a more accurate assessment of what kind of glasses prescription is required.
A Cancer man is conservative just enough to know that initiative is important, but often fails to show it before he feels safe to do so. His partners need to make the first move, but still doing it subtly to let him still feel like he is leading the way. This is a complex individual, very sensitive, shy and overly protective of his loved ones. When he prefers women, he will subconsciously search for the ideal wife and mother.

^ Catassi C, Bai J, Bonaz B, Bouma G, Calabrò A, Carroccio A, Castillejo G, Ciacci C, Cristofori F, Dolinsek J, Francavilla R, Elli L, Green P, Holtmeier W, Koehler P, Koletzko S, Meinhold C, Sanders D, Schumann M, Schuppan D, Ullrich R, Vécsei A, Volta U, Zevallos V, Sapone A, Fasano A (2013). "Non-celiac gluten sensitivity: the new frontier of gluten related disorders". Nutrients (Review). 5 (10): 3839–3853. doi:10.3390/nu5103839. ISSN 2072-6643. PMC 3820047. PMID 24077239.
Prevention and treatment involve maintaining a healthy diet, regular physical exercise, a normal body weight, and avoiding use of tobacco.[2] Control of blood pressure and maintaining proper foot care are important for people with the disease.[2] Type 1 DM must be managed with insulin injections.[2] Type 2 DM may be treated with medications with or without insulin.[12] Insulin and some oral medications can cause low blood sugar.[13] Weight loss surgery in those with obesity is sometimes an effective measure in those with type 2 DM.[14] Gestational diabetes usually resolves after the birth of the baby.[15]

The earliest surviving work with a detailed reference to diabetes is that of Aretaeus of Cappadocia (2nd or early 3rd century CE). He described the symptoms and the course of the disease, which he attributed to the moisture and coldness, reflecting the beliefs of the "Pneumatic School". He hypothesized a correlation between diabetes and other diseases, and he discussed differential diagnosis from the snakebite, which also provokes excessive thirst. His work remained unknown in the West until 1552, when the first Latin edition was published in Venice.[110]
The LD50 for THC (Delta 9 Tetrahydrocannabinol) is not precisely known, as there have been no recorded fatalities. Hash oil can contain up to 80% THC though up to 99% with other methods of extraction. While health issues of the lungs may be exacerbated by use of hash oil, it is not known to cause side effects not already found in other preparations of cannabis.[citation needed]

Royal Queen Seeds CBD Oil offers a convenient, discreet and quick way to dose yourself with a bit of CBD, no matter your situation or where you are. All of our CBD oil is created using organically grown hemp sourced from right here in Europe, extracted using the latest CO² techniques. It means our oil is 100% natural, offering pure and strong CBD. All you need to do as drop you dose under your tongue or in your food, and away you go! The CBD oil from RQS is full spectrum.
Elixinol has a wide range of products, but their CBD Tincture does the trick. It’s the cream of the crop regarding CBD oils and that reflects in its price. One dropper (1mg) from the 300 series contains 10mg of CBD. This allows you to get precise amounts of CBD and no guess work is required. Elixinol has received numerous awards for their products and extraction process.
However, if it was sourced from actual marijuana (i.e. cannabis that contains more than 2% THC by volume), then it is technically illegal. Most of the best CBD oils for pain that you find in dispensaries in states like Colorado, California, and Washington (as well as other states where weed is legal) will have been extracted from marijuana plants — not industrial hemp plants. Unfortunately, this means that these products are not allowed to be sold online and shipped across state lines to “non-legal” states.
^ Rostom A, Dubé C, Lewin G, Tsertsvadze A, Barrowman N, Code C, Sampson M, Moher D (March 2007). "Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: a systematic review prepared for the U.S. Preventive Services Task Force". Annals of Internal Medicine. 146 (5): 376–89. doi:10.7326/0003-4819-146-5-200703060-00010. PMID 17339623.
^ Narayanan L, Fritzell JA, Baker SM, Liskay RM, Glazer PM (April 1997). "Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2". Proceedings of the National Academy of Sciences of the United States of America. 94 (7): 3122–27. Bibcode:1997PNAS...94.3122N. doi:10.1073/pnas.94.7.3122. PMC 20332. PMID 9096356.
The primary complications of diabetes due to damage in small blood vessels include damage to the eyes, kidneys, and nerves.[31] Damage to the eyes, known as diabetic retinopathy, is caused by damage to the blood vessels in the retina of the eye, and can result in gradual vision loss and eventual blindness.[31] Diabetes also increases the risk of having glaucoma, cataracts, and other eye problems. It is recommended that diabetics visit an eye doctor once a year.[32] Damage to the kidneys, known as diabetic nephropathy, can lead to tissue scarring, urine protein loss, and eventually chronic kidney disease, sometimes requiring dialysis or kidney transplantation.[31] Damage to the nerves of the body, known as diabetic neuropathy, is the most common complication of diabetes.[31] The symptoms can include numbness, tingling, pain, and altered pain sensation, which can lead to damage to the skin. Diabetes-related foot problems (such as diabetic foot ulcers) may occur, and can be difficult to treat, occasionally requiring amputation. Additionally, proximal diabetic neuropathy causes painful muscle atrophy and weakness.
One idea about why people with cancer are blamed or stigmatized, called the just-world hypothesis, is that blaming cancer on the patient's actions or attitudes allows the blamers to regain a sense of control. This is based upon the blamers' belief that the world is fundamentally just and so any dangerous illness, like cancer, must be a type of punishment for bad choices, because in a just world, bad things would not happen to good people.[199]

Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.

In the United States and some other cultures, cancer is regarded as a disease that must be "fought" to end the "civil insurrection"; a War on Cancer was declared in the US. Military metaphors are particularly common in descriptions of cancer's human effects, and they emphasize both the state of the patient's health and the need to take immediate, decisive actions himself rather than to delay, to ignore or to rely entirely on others. The military metaphors also help rationalize radical, destructive treatments.[195][196]

I started with the 500mg tincture to test the product and now I purchase the 3000mg. Its good value and really helps my daily anxiety. The 500mg I had to take every 2 hours but the 3000mg is stronger and lasts me 4-5 hours. I never leave reviews but promised one of the customer service reps I would based on how helpful they were. Company seems legit.

Earlier and accurate diagnosis can help to prevent irreversible damage and disability. Properly guided programs of exercise and rest, medications, physical therapy, and surgery options can idealize long-term outcomes for those with arthritis. Exercise and exercise routines can be helpful in providing joint stability by strengthening the musculoskeletal system while improving balance. Physical therapists can provide the care needed for properly guided exercise regimens.


Truth be told, one of the biggest draws to using CBD oil for pain has been the fact that it has little distinguishable side-effects or contraindications with other medications. In fact, in a massive report that was published by the World Health Organization during last year’s 2017 Expert Committee on Drug Dependence, it was (finally) declared to the world that CBD is a “safe, well tolerated [compound, which] is not associated with any significant adverse public health effects.”


I am very interested in trying one of these CBD oils. I’m not too familiar with them, other than a few things I researched. But I’ve never tried any before. I have congestive heart failure, and cirrhosis of the liver. I have really bad stomach pain/nausea most of the time to where I can’t even get out of bed! Also muscle and joint pain, anxiety/panic attacks, and depression. I’m hoping that I’ve found something that will help with these awful symptoms. If anyone could please help me with choosing the best CBD oil to start with it would be greatly appreciated!! So far I think I’m leaning more towards the PureKana, but haven’t looked into the prices yet. Any recommendations please and thank you?!
The word mellitus (/məˈlaɪtəs/ or /ˈmɛlɪtəs/) comes from the classical Latin word mellītus, meaning "mellite"[114] (i.e. sweetened with honey;[114] honey-sweet[115]). The Latin word comes from mell-, which comes from mel, meaning "honey";[114][115] sweetness;[115] pleasant thing,[115] and the suffix -ītus,[114] whose meaning is the same as that of the English suffix "-ite".[116] It was Thomas Willis who in 1675 added "mellitus" to the word "diabetes" as a designation for the disease, when he noticed the urine of a diabetic had a sweet taste (glycosuria). This sweet taste had been noticed in urine by the ancient Greeks, Chinese, Egyptians, Indians, and Persians.
I'm here to testify about what doctorlucky did for me. I have been suffering from (GENITAL HERPES VIRUS) disease for the past 4 months and had constant pain and inching, especially in my private part. During the first year, I had faith in God that i would be cured someday.This disease started circulating all over my body and I have been taking treatment from my doctor, few weeks ago I came across a testimony of rose anderson on the internet testifying about a Man called doctorlucky on how he cured her from 7 years HSV 2. And she also gave the email address of this man, advise anybody to contact him for help on any kind of diseases that he would be of help, so I emailed him telling him about my (HSV 2) he told me not to worry that I was going to be cured!! Well, I never doubted him I have faith he can cure me too,doctorlucky prepared and sent me Healing Oil, Soap, roots and herbs which I took. In the first one week, I started experiencing changes all over me, after four weeks of using his Roots/ Herbs, Oil and Soap, I was totally cured. no more inching , pain on me anymore as doctorlucky assured me. After some time I went to my doctor to do another test behold the result came out negative. So friends my advise is if you have such disease or know anyone who suffers from it or any other disease like HPV, HBV, HIV, ALS, HBP, CANCER etc. you can contact doctorlucky for help via email} or call or whatsapp him on +393510598611 Thanks once again doctorlucky for making me a happy woman again.
I have had several neurological conditions like Bells Palsy three times, double vision, paralysis of left side of tongue. I have a lot of relief whenever I have pain by taking an inflamattory drug etoshine90 mg. Presently I have started taking Steroids for my facial palsy. The various pains I was having on the left side of neck, below the left ear, dizziness, pain around the head have subsided immidiately after the first dose of prendisolone 60 mg.I have read that CBD hemp oil can be useful for my condition of neurological and inflammation issues. My question is what concentrate (mg) of the oil should I take and for how long. Any brand that you may suggest that are available in the UK. Thank you.
Everything you need to know about marijuana (cannabis) Marijuana, or cannabis, is the most commonly used illicit drug in the world. It alters the mood and affects nearly every organ in the body. With at least 120 active compounds, marijuana may have health benefits as well as risks. We describe these, addiction, and withdrawal. Learn more about cannabis here. Read now
I have been giving my 9 year old German Shepard the 500mg tincture a few times per day and he has really taken to it. Hes suffered from hip pain I believe arthritis and getting up off the floor and stairs have been an issue. After taking this oil We noticed immediate results. Im a believer in CBD and if Arnold could speak he would thank us for giving him this CBD. 5 stars
Hello Roy,We will attempt to help you as much as possible.As you know CBD is a new treatment option so there are almost no scientific studies and very few case studies available. However as a general rule the best thing to do is just to start.We say this because everyones body metabolizes CBD at different rates. So the best way to find the proper dosage for you is just to start. The good news is that feeling sleepy is about the only side effect of overdosing CBD, so experimentation is pretty safe.What we recommend on our site is to start with 25mg of CBD taken as often as you need it throughout the day. If you find this works stick with it. If you find you need more, or are having to take it too many times during the day, then take more such as 50mg with each serving.Which oil should you use that will ship to the UK? We have reviewed all the top CBD oil products and have found Endoca to be the best and most powerful oil on the market. If you are going to use CBD hemp oil we recommend using raw CBD oil. This is the most natural and has the highest amount of plant constituents present which increases effectiveness.The best oil to start with is Endoca Raw Hemp Oil 2000mg. If taking 50mg a day this tube will last you 40 days. If you are taking 200mg a day you will need to purchase 3 tubes per month.Read the full review here: https://cbdoilreview.org/endoca-raw-hemp-oil-2000mg/Buy the product here: https://cbdoilreview.org/product/endoca-raw-hemp-oil-2000mg/Endoca ships to the UK from their European headquarters so you are good to go there. If you have any other questions please contact us using the form below or give us a call, we are happy to help!

The Arthritis Foundation is the only national voluntary health organization whose purpose is directed solely to all forms of arthritis. The Arthritis Foundation has national and international programs involving support for scientific research, public information and education for affected patients and their families, training of specialists, public awareness, and local community assistance.


The equivalency factor is not designed to compare the effects of cannabis oil to dried cannabis, or provide dosage information. For many patients, consuming cannabis orally will produce much stronger effects than inhaling it. For example, when considering a product that has an equivalency factor of 12ml of oil to 1 gram of dried cannabis, and a patient who usually consumes 1 gram of dried product a day, this patient will likely use less than 12 ml of oil per day. Even for patients who have previous experience of using cannabis oil, it is recommend that you start with a low dose and go slow.
Take your medicine. If your diabetes can’t be controlled with diet, exercise, and weight control, your doctor may recommend medicine or insulin. Most people who have type 2 diabetes start with an oral medicine (taken by mouth). Oral medicines can make your body produce more insulin. They also help your body use the insulin it makes more efficiently. Some people need to add insulin to their bodies with insulin injections, insulin pens, or insulin pumps. Always take medicines exactly as your doctor prescribes. Oral medicine doesn’t work for everyone. It is not effective in the treatment of type 1 diabetes. Insulin therapy is necessary for all people who have type 1 diabetes and for some people who have type 2 diabetes. If you need insulin, you’ll have to give yourself a shot (either with a syringe or with an insulin pen). Your doctor will tell you which kind of medicine you should take and why.
Periodontal disease is the most common dental disease affecting those living with diabetes, affecting nearly 22% of those diagnosed. Especially with increasing age, poor blood sugar control increases the risk for gum problems.  In fact, people with diabetes are at a higher risk for gum problems because of poor blood sugar control. As with all infections, serious gum disease may cause blood sugar to rise. This makes diabetes harder to control because you are more susceptible to infections and are less able to fight the bacteria invading the gums.
Some slow-growing cancers are particularly common, but often are not fatal. Autopsy studies in Europe and Asia showed that up to 36% of people have undiagnosed and apparently harmless thyroid cancer at the time of their deaths and that 80% of men develop prostate cancer by age 80.[178][179] As these cancers do not cause the patient's death, identifying them would have represented overdiagnosis rather than useful medical care.
My husband has RSD and we are considering CBD oil -= I would ask at Hempmed because the spray won't have enough in it. Our dgt';s friend has ovarian cancer and it is shrinking her tumors but the spray would never have been enough. I would get CBD oil and check with Hempmeds to see what they suggest. It isn't cheap but it does work. LOW dose Naltrexone about 4.5 mg is very helpful for RSD and is usually used for getting people off of drugs but is working on turning off the glial cells that surround the nerve that is causing the nerve to scream in pain. We are also using PeaPure that is out of the Netherlands and we are seeing a response, even though small. His other leg touched the painful leg without causing more severe pain. That is progress. We also are using Poison Ivy Cream through Meadowlake Farms that has helped the burning surface pain. Change your diet and get rid of Gluten and Sugar, anything that causes inflammation. This is to allow your own body to work. Absolutely do not use any pain killers as it will turn up your pain. all the Hydrocodone, etc causes neural inflammation and so it will keep cascading higher your pain. Hope this is helpful. Mary
Although delta-9-tetrahydrocannabinol (known as THC) is the primary psychoactive ingredient, other known compounds with biologic activity are cannabinol, cannabidiol, cannabichromene, cannabigerol, tetrahydrocannabivarin and delta-8-THC. Cannabidiol (CBD) is thought to have significant pain-relieving and anti-inflammatory activity without the psychoactive effect of delta-9-THC. (2)
Diet. A diet high in fat, calories, and cholesterol increases your risk of diabetes. A poor diet can lead to obesity (another risk factor for diabetes) and other health problems. A healthy diet is high in fiber and low in fat, cholesterol, salt, and sugar. Also, remember to watch your portion size. How much you eat is just as important as what you eat.
Normal cells may become cancer cells. Before cancer cells form in tissues of the body, the cells go through abnormal changes called hyperplasia and dysplasia. In hyperplasia, there is an increase in the number of cells in an organ or tissue that appear normal under a microscope. In dysplasia, the cells look abnormal under a microscope but are not cancer. Hyperplasia and dysplasia may or may not become cancer.
Cancer cells differ from normal cells in many ways that allow them to grow out of control and become invasive. One important difference is that cancer cells are less specialized than normal cells. That is, whereas normal cells mature into very distinct cell types with specific functions, cancer cells do not. This is one reason that, unlike normal cells, cancer cells continue to divide without stopping.

Laser therapy uses high-intensity light to treat cancer by shrinking or destroying tumors or precancerous growths. Lasers are most commonly used to treat superficial cancers that are on the surface of the body or the lining of internal organs. It is used to treat basal cell skin cancer and the very early stages of others like cervical, penile, vaginal, vulvar, and non-small cell lung cancer. It is often combined with other treatments, such as surgery, chemotherapy, or radiation therapy. Laser-induced interstitial thermotherapy (LITT), or interstitial laser photocoagulation, uses lasers to treat some cancers using hyperthermia, which uses heat to shrink tumors by damaging or killing cancer cells. Laser are more precise than surgery and cause less damage, pain, bleeding, swelling, and scarring. A disadvantage is surgeons must have specialized training. It may be more expensive than other treatments.[162]
When Dan Hamilton was diagnosed with T1D in 1972, the doctor told him he wouldn’t live past 50. Fast forward 45 years, and Dan is strong and healthy at 59. He credits his health to the advancements in treatment and care over the years. He has been an early adopter of every technology that has come along, and exercises regularly as part of a healthy lifestyle.
There are two possible exceptions to this. The first is that some people, for unknown reasons, just react differently to CBD. According to Dr. Chin, about 5% of people say they feel altered after taking CBD. "Usually they're the same people who have side effects from Advil or Tylenol," she says. You never know how your body will react to any new supplement, so when taking CBD for the first time, do so safely under supervision.
^ Baldassarre G, Battista S, Belletti B, Thakur S, Pentimalli F, Trapasso F, Fedele M, Pierantoni G, Croce CM, Fusco A (April 2003). "Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma". Molecular and Cellular Biology. 23 (7): 2225–38. doi:10.1128/MCB.23.7.2225-2238.2003. PMC 150734. PMID 12640109./

Deaths from cancer were 5.8 million in 1990.[171] Deaths have been increasing primarily due to longer lifespans and lifestyle changes in the developing world.[22] The most significant risk factor for developing cancer is age.[172] Although it is possible for cancer to strike at any age, most patients with invasive cancer are over 65.[172] According to cancer researcher Robert A. Weinberg, "If we lived long enough, sooner or later we all would get cancer."[173] Some of the association between aging and cancer is attributed to immunosenescence,[174] errors accumulated in DNA over a lifetime[175] and age-related changes in the endocrine system.[176] Aging's effect on cancer is complicated by factors such as DNA damage and inflammation promoting it and factors such as vascular aging and endocrine changes inhibiting it.[177]


Gouty arthritis develops as the result of uric acid buildup in the bloodstream. The uric acid forms crystals which cause acute inflammation in a joint. The big toe, ankle, knee, and elbow are the most common joints affected. A gout attack can be acutely painful. The inflamed joint becomes red and very sensitive to touch. Gout attacks are most often treated with medicine rather than surgery. Long term, many patients develop soft tissue masses (tophi) over the affected joints.
Lisa Hamilton, a jeweler and doula in Brooklyn, NY, knows about the side effects. She recently tried CBD for the shoulder pain that plagued her five years after an accident. Her doctor certified that she was in chronic pain, which under New York State law allowed her to buy from a state dispensary. One Friday, she swallowed two 10-mg capsules, the amount recommended at the dispensary, then took another two on Saturday. “By Sunday, it felt like I’d gotten hit by a truck. Every muscle and joint ached,” Hamilton says. She cut back to one pill a day the following week, but still felt hungover. She stopped after that.
Elements of the history of the disorder guide diagnosis. Important features are speed and time of onset, pattern of joint involvement, symmetry of symptoms, early morning stiffness, tenderness, gelling or locking with inactivity, aggravating and relieving factors, and other systemic symptoms. Physical examination may confirm the diagnosis, or may indicate systemic disease. Radiographs are often used to follow progression or help assess severity.
Pharmacists have since moved to metric measurements, with a drop being rounded to exactly 0.05 mL (50 μL, that is, 20 drops per milliliter) - https://en.wikipedia.org/wiki/Drop_(unit)1oz is 30 mL1000mg/30mL = 33.3 mg/mL CBD concentration20 drops * .05 mL/drop = 1mL10 drops * .05 mL/drop = .5mLyou take 33.3 mg in the morning and 16.65mg at nightI might suggest taking 50mg in the morning: 50mg / 33.3 mg/mL = 1.50 mL 30 dropstry it for a couple days and see how it helps
The WHO estimates that diabetes mellitus resulted in 1.5 million deaths in 2012, making it the 8th leading cause of death.[12][101] However another 2.2 million deaths worldwide were attributable to high blood glucose and the increased risks of cardiovascular disease and other associated complications (e.g. kidney failure), which often lead to premature death and are often listed as the underlying cause on death certificates rather than diabetes.[101][104] For example, in 2017, the International Diabetes Federation (IDF) estimated that diabetes resulted in 4.0 million deaths worldwide,[8] using modeling to estimate the total number of deaths that could be directly or indirectly attributed to diabetes.[8]
Cannabis has been an ally of humankind since before the written word, providing fiber for cordage and cloth, seeds for nutrition, and roots, leaves and flowers for ritual and healing. During the Neolithic period, our ancestors discovered uses for every part of cannabis, which was one of the first agricultural crops to be cultivated and harvested some 12,000 years ago.
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