A rheumatologist is a medical doctor who specializes in the nonsurgical treatment of rheumatic illnesses, especially arthritis. Rheumatologists have special interests in unexplained rash, fever, arthritis, anemia, weakness, weight loss, fatigue, joint or muscle pain, autoimmune disease, and anorexia. They often serve as consultants, acting like medical detectives at the request of other doctors.
Along with its better-known counterpart, THC (delta-9-tetrahydrocannabinol, the chemical that produces the marijuana high), CBD is one of more than 400 compounds found in the oils of cannabis plant species, which include marijuana and hemp. Unlike THC, CBD will not make you high. That said, this doesn’t mean CBD is not at all psychoactive, as many assert, says Jahan Marcu, Ph.D., director of experimental pharmacology and behavior at the International Research Center on Cannabis and Mental Health in New York City: “CBD does change cognition. It affects mood, which is why people take it for anxiety. And some find that it makes them more alert.”
Gestational diabetes mellitus (GDM) resembles type 2 DM in several respects, involving a combination of relatively inadequate insulin secretion and responsiveness. It occurs in about 2–10% of all pregnancies and may improve or disappear after delivery.[49] However, after pregnancy approximately 5–10% of women with GDM are found to have DM, most commonly type 2.[49] GDM is fully treatable, but requires careful medical supervision throughout the pregnancy. Management may include dietary changes, blood glucose monitoring, and in some cases, insulin may be required.
Cancer screening is not available for many types of cancers. Even when tests are available, they may not be recommended for everyone. Universal screening or mass screening involves screening everyone.[129] Selective screening identifies people who are at higher risk, such as people with a family history.[129] Several factors are considered to determine whether the benefits of screening outweigh the risks and the costs of screening.[128] These factors include:
Epigenetic alterations occur frequently in cancers. As an example, one study listed protein coding genes that were frequently altered in their methylation in association with colon cancer. These included 147 hypermethylated and 27 hypomethylated genes. Of the hypermethylated genes, 10 were hypermethylated in 100% of colon cancers and many others were hypermethylated in more than 50% of colon cancers.[80]

Marijuana enthusiasts will always hold a special place in their heart for the big, beautiful, healthy bud cut fresh from plant ready for a good ole fashioned smoke. However, since the passage of medical and recreational marijuana in Colorado, cannabis consumption methods have evolved rapidly and the popularity of concentrated hash oil products has surged.
The classic symptoms of untreated diabetes are unintended weight loss, polyuria (increased urination), polydipsia (increased thirst), and polyphagia (increased hunger).[20] Symptoms may develop rapidly (weeks or months) in type 1 DM, while they usually develop much more slowly and may be subtle or absent in type 2 DM. Other symptoms of diabetes mellitus include weight loss and tiredness.[21]

Bonn-Miller also explained that it's imperative to exhaust the traditional and established front-line treatments that are available before seeking out these products. "CBD is not really a first-line treatment for anything," he said. "You don’t want situations where somebody says, 'I have cancer I'm going to forgo chemotherapy because I read something about CBD or THC helping with cancer.'" That's not a good idea, Bonn-Miller said. "Not only is the science not there, but you may end up worse off."
For instance, some people report a sense of calm and peace; others report increased anxiety levels and unpleasant sensations. The intensity of these symptoms will largely depend on an individual’s body composition. In addition, marijuana strains feature different levels of oil concentration that also determines the intensity of the outcomes that a user feels after consumption. Some strains are recommended to produce less profound symptoms and reactions.
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The use of cannabis for pain relief dates back to ancient China, according to a report published in the journal Cannabis and Cannabinoid Research. It’s thought that CBD oil might help ease chronic pain in part by reducing inflammation. In addition, CBD oil is said to promote sounder sleep and, in turn, treat sleep disruption commonly experienced by people with chronic pain.
If you have been recently diagnosed with a specific type of arthritis, you likely don't know much about it or what to expect going forward. Only If you know someone with arthritis will you have some idea. The most difficult aspect to grasp may be that there is an uncertainty and unpredictability that comes with the diagnosis of one of the types of arthritis. Even the pain is variable.
John Staughton is a traveling writer, editor, and publisher who earned his English and Integrative Biology degrees from the University of Illinois in Champaign, Urbana (USA). He is the co-founder of a literary journal, Sheriff Nottingham, and calls the most beautiful places in the world his office. On a perpetual journey towards the idea of home, he uses words to educate, inspire, uplift and evolve.
Epigenetic alterations are functionally relevant modifications to the genome that do not change the nucleotide sequence. Examples of such modifications are changes in DNA methylation (hypermethylation and hypomethylation), histone modification[78] and changes in chromosomal architecture (caused by inappropriate expression of proteins such as HMGA2 or HMGA1).[79] Each of these alterations regulates gene expression without altering the underlying DNA sequence. These changes may remain through cell divisions, last for multiple generations and can be considered to be epimutations (equivalent to mutations).
Splinting. Injections are usually combined with splinting of the affected joint. The splint helps support the affected joint to ease the stress placed on it from frequent use and activities. Splints are typically worn during periods when the joints hurt. They should be small enough to allow functional use of the hand when they are worn. Wearing the splint for too long can lead to muscle deterioration (atrophy). Muscles can assist in stabilizing injured joints, so atrophy should be prevented.

Mike, what kind of breast cancer (invasive ductal, I presume)? How many of her lymph nodes were positive? How big was the primary tumor? Reason I ask is that in women with Stage I or IIA tumors that are estrogen-and progesterone-receptor-positive and HER2-negative (ER+/PR+/HER2-) with three or fewer positive lymph nodes, there is a genomic assay test on a sample of the tumor, called OncotypeDX, that will tell doctors whether chemo is necessary or would even work at all. Medicare covers that test 100%.That type of breast cancer mentioned above, which I had as Stage IA, is treated in postmenopausal women with anti-estrogen drugs called aromatase inhibitors(aka AIs: anastrazole, letrozole, or exemestane)which have as a side effect joint pain. CBD oil is effective for this joint pain it is not, I repeat, NOT a substitute for chemo, radiation or these anti-estrogen drugs.So don’t assume your mom’s cancer will require chemo; but if it does, CBD helps with those side effects as well. If she lives in a state where medical marijuana is legal, there are doctors who sub-specialize in certifying applications for a medical marijuana card, and in the interim before the card is issued can advise as to the appropriate dose of CBD oil (legal and over-the-counter in all 50 states). Some (though not most) medical oncologists will certify their own patients’ medical marijuana card applications so she need not seek out another doctor; and will advise the appropriate dose for her symptoms. Once she gets her card, the “budtenders” in the licensed dispensaries can advise her as to the right CBD product (with or without THC), strength, and dosage. If she lives in a state where recreational weed is legal, the “budtenders” in the marijuana shops can steer her to the right strength of CBD oil and the right dosage.
Uric acid is formed as the body breaks down purines, a substance found in human cells and in many foods. Some people have high levels of uric acid because they naturally produce more than is needed or the body can’t get rid of the uric acid quickly enough. In some people the uric acid builds up and forms needle-like crystals in the joint, resulting in sudden spikes of extreme joint pain, or a gout attack. Gout can come and go in episodes or, if uric acid levels aren’t reduced, it can become chronic, causing ongoing pain and disability.
Chemotherapy is the treatment of cancer with one or more cytotoxic anti-neoplastic drugs (chemotherapeutic agents) as part of a standardized regimen. The term encompasses a variety of drugs, which are divided into broad categories such as alkylating agents and antimetabolites.[144] Traditional chemotherapeutic agents act by killing cells that divide rapidly, a critical property of most cancer cells.
Physical trauma resulting in cancer is relatively rare.[64] Claims that breaking bones resulted in bone cancer, for example, have not been proven.[64] Similarly, physical trauma is not accepted as a cause for cervical cancer, breast cancer or brain cancer.[64] One accepted source is frequent, long-term application of hot objects to the body. It is possible that repeated burns on the same part of the body, such as those produced by kanger and kairo heaters (charcoal hand warmers), may produce skin cancer, especially if carcinogenic chemicals are also present.[64] Frequent consumption of scalding hot tea may produce esophageal cancer.[64] Generally, it is believed that cancer arises, or a pre-existing cancer is encouraged, during the process of healing, rather than directly by the trauma.[64] However, repeated injuries to the same tissues might promote excessive cell proliferation, which could then increase the odds of a cancerous mutation.

I suffer from severe anxiety characterized by random panic attacks depression. Medication has not been helping. We moved and I stopped doing all the things I use to enjoy. Within days of using this product I was back doing the things I love. I cannot believe the amount of relief I get from this miraculous product. Zero unpleasant taste easy to take I have no complaints other than I wish I wouldve found this product years ago. Ive recommended it to everyone I know and I dont plan on ever being without it from now on. Looking forward to completely weening off my medication because I believe this product will help me more with no side affects. Do yourself a favor and start taking this there is a solution and this is it
At present, the American Diabetes Association does not recommend general screening of the population for type 1 diabetes, though screening of high risk individuals, such as those with a first degree relative (sibling or parent) with type 1 diabetes should be encouraged. Type 1 diabetes tends to occur in young, lean individuals, usually before 30 years of age; however, older patients do present with this form of diabetes on occasion. This subgroup is referred to as latent autoimmune diabetes in adults (LADA). LADA is a slow, progressive form of type 1 diabetes. Of all the people with diabetes, only approximately 10% have type 1 diabetes and the remaining 90% have type 2 diabetes.
Periodontal disease is the most common dental disease affecting those living with diabetes, affecting nearly 22% of those diagnosed. Especially with increasing age, poor blood sugar control increases the risk for gum problems.  In fact, people with diabetes are at a higher risk for gum problems because of poor blood sugar control. As with all infections, serious gum disease may cause blood sugar to rise. This makes diabetes harder to control because you are more susceptible to infections and are less able to fight the bacteria invading the gums.
Diabetic retinopathy (eye problems). This affects the part of your eye called the retina. It is the part of the eye that is sensitive to light and sends messages to your brain about what you see. Diabetes can damage and weaken the small blood vessels in the retina. When the blood vessels of your retina are damaged, fluid can leak from them and cause swelling in your macula. The macula is the part of the retina that gives you sharp, clear vision. Swelling and fluid can cause blurry vision. This makes it hard for you to see. If retinopathy gets worse, it may lead to blindness. Laser surgery can often be used to treat or slow down retinopathy if found early. People who have diabetes should have an eye exam once a year. See your doctor if you have blurry vision for more than 2 days, sudden loss of vision in 1 or both eyes, black or moving gray spots often called “floaters,” flashing lights, or pain or pressure in your eyes.
^ Piwernetz K, Home PD, Snorgaard O, Antsiferov M, Staehr-Johansen K, Krans M (May 1993). "Monitoring the targets of the St Vincent Declaration and the implementation of quality management in diabetes care: the DIABCARE initiative. The DIABCARE Monitoring Group of the St Vincent Declaration Steering Committee". Diabetic Medicine. 10 (4): 371–77. doi:10.1111/j.1464-5491.1993.tb00083.x. PMID 8508624.
To explain what hemoglobin A1c is, think in simple terms. Sugar sticks, and when it's around for a long time, it's harder to get it off. In the body, sugar sticks too, particularly to proteins. The red blood cells that circulate in the body live for about three months before they die off. When sugar sticks to these hemoglobin proteins in these cells, it is known as glycosylated hemoglobin or hemoglobin A1c (HBA1c). Measurement of HBA1c gives us an idea of how much sugar is present in the bloodstream for the preceding three months. In most labs, the normal range is 4%-5.9 %. In poorly controlled diabetes, its 8.0% or above, and in well controlled patients it's less than 7.0% (optimal is <6.5%). The benefits of measuring A1c is that is gives a more reasonable and stable view of what's happening over the course of time (three months), and the value does not vary as much as finger stick blood sugar measurements. There is a direct correlation between A1c levels and average blood sugar levels as follows.
My order has shipped and should be here on the 31st. I am so excited. I got an anoxic brain injury during an open heart surgery. Since then I have had an amazing amount of muscle and nerve pain. I ordered the 500mg bottle. I was told to start low and go higher if I need it. So excited to receive it. I am praying it works for my pain. I will let you know my progress. Thank You
Cataracts and glaucoma are also more common among diabetics. It is also important to note that since the lens of the eye lets water through, if blood sugar concentrations vary a lot, the lens of the eye will shrink and swell with fluid accordingly. As a result, blurry vision is very common in poorly controlled diabetes. Patients are usually discouraged from getting a new eyeglass prescription until their blood sugar is controlled. This allows for a more accurate assessment of what kind of glasses prescription is required.
Scientifically, industrial Hemp and Marijuana are the same plant, with a genus and species name of Cannabis Sativa. They have a drastically different genetic profile though. Industrial Hemp is always a strain of Cannabis sativa, while marijuana can be Cannabis sativa, Cannabis indica, or Cannabis ruderalis. The major difference is how industrial hemp has been bred compared to a marijuana form of Cannabis sativa. Typically speaking, industrial hemp is very fibrous, with long strong stalks, and barely has any flowering buds, while a marijuana strain of Cannabis sativa will be smaller, bushier, and full of flowering buds. However, newer industrial hemp varieties in the USA are being bred to have more flowers and higher yields of cannabinoids and terpenes, such as our Kentucky hemp we’re now using!

My dad has severe advanced stage Dementia. Will CBD oil help him at this point? He is now refusing to eat any solid food, but will accept most drinks.In addition, he has lost a great deal of weight even though they're giving him Mega Shakes containing a full meals worth of proteins, etc. He gets at least 4 of these a day..some which he refuses. Is his Dementia too far gone for CBD oils to help him?


Greetings to you all, i am Falcao Roland,i am broadcasting about how Dr Olori saved my life, i was infected with Genital Herpes for A year, my medical Dr told me that there i no total cure and i began to take pill to sustain my self. One day i went to see my medical doctor and i saw a lady who was extremely happy and i asked to know the reason of her happiness and she told me that she was infected with simplex HERPES disease and a herbal doctor called Dr Olori cured her with herbal medicine, i did not believe so i asked my medical doctor to know if she was truly confirmed Herpes positive before, and my medical doctor told me yes that a miracle just happened so i asked her to give me the details of the Dr so i could ask him if he could also cure mine and she gave me Dr Olori Email: droloriherbalcenter gmail com I contacted him that very evening and i explained my problem to him and he prepared a medicine and send to me, when i received the medicine he told me how to take it for a period of days and i took it exactly as he said and went for a medical test i was surprise to see my test result as herpes negative. I am so happy, my family and friends that rejected me are back, thank you God. I guarantee you that Dr Olori has solution to all kind of problem if you are facing any stress you can contact him via email droloriherbalcenter gmail com or droloriherbalcenter yahoo com, call +2349053311935.
I have struggled for years with irritable bowel syndrome and could literally find no relief. Atleast once a day I would have a moment where I would have to run to the bathroom and that became embarrassing and also anxiety filled. I have tried changing my diet avoiding certain foods eliminating dairy and also taking an anti spasmodic that my gastroenterologist gave me however they have not worked. It got to the point where I had severe anxiety of eating any foods and I lost weight. When I started the CBD I immediately felt better and my stomach did not make any more rumbles or had to run to the bathroom. Ive been able to bring back a lot of different kinds of food to my diet and I feel much better about eating because I know I wont have any symptoms. They basically disappeared

Epigenetic alterations occur frequently in cancers. As an example, one study listed protein coding genes that were frequently altered in their methylation in association with colon cancer. These included 147 hypermethylated and 27 hypomethylated genes. Of the hypermethylated genes, 10 were hypermethylated in 100% of colon cancers and many others were hypermethylated in more than 50% of colon cancers.[80]
Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can't give more specific advice in this forum, but there is help!

Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.


Chemotherapy is the treatment of cancer with one or more cytotoxic anti-neoplastic drugs (chemotherapeutic agents) as part of a standardized regimen. The term encompasses a variety of drugs, which are divided into broad categories such as alkylating agents and antimetabolites.[144] Traditional chemotherapeutic agents act by killing cells that divide rapidly, a critical property of most cancer cells.
Trichomes are fragile structures that easily break off of the cannabis flower. Even rough handling is enough to shake off the trichomes. Making hashish or “kif” (hashish powder) involves manually removing the resinous trichomes by agitating the flower. Sometimes heat or pressure is applied to partially melt the trichomes together, turning the resin into a congealed slab, referred to as rosin, which can be smoked or ingested.
^ Rutjes, Anne Ws; Nüesch, Eveline; Sterchi, Rebekka; Kalichman, Leonid; Hendriks, Erik; Osiri, Manathip; Brosseau, Lucie; Reichenbach, Stephan; Jüni, Peter (2009-10-07). "Transcutaneous electrostimulation for osteoarthritis of the knee" (PDF). The Cochrane Database of Systematic Reviews (4): CD002823. doi:10.1002/14651858.CD002823.pub2. ISSN 1469-493X. PMID 19821296.
REM behavior disorder: REM behavior disorder (RBD) is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep. For many, RBD is a symptom of a larger, more serious condition or disorder, such as Alzheimer’s disease or PTSD. CBD oil minimizes the symptoms of RBD, and also alleviates the anxiety and painful symptoms that often accompany disorders that lead to RBD.
The card will be valid for two years from the date it is issued. The expiration date will be printed on the front of the card. After that time, you will need to again consult with your physician and request that they update and confirm your information into the registry. Please plan to allow 15 business days to process your information, print your card and have it ready for pick-up from the closest of the 20 Public Health Offices approved to distribute them to the address you list as your residence in the registry. 
It took almost one year for my first real outbreak but it was the hardest thing in the world to get along with. I felt so unwanted and dirty. I tried many formulas, suggestions, methods to get rid of it permanently. Booked appointment with many doctors, professionals, even religiously until I started getting away spiritually and still it won't go. The worst is my outbreaks occurs within short period and take as long as even weeks to go away. I was at last placed on antiviral treatment which is a good treatment but for how long? I prayed every four times a day for God to cure me miraculously or direct me to cure because I know there is. During outbreaks I thought it's the end of the world but it's not, with time I will become normal again. I started trying fruits and herbs, take herbal produced, and with time became very interested in herbs. I read blogs, websites, and comments on herbs and built a stronger hope. I saw comments and decided to try Dr Utu African Traditional Herbal meds. I know of one mr Brown who was HIV and now brags he was cured of HIV with Dr Utu traditional meds but never give it a thought because I believed HIV already has a cure and never think it through or make a research. And for herpes my doctor told me that there is no known cure. When I saw testimonies of his Herpes cure on sites. I copied his contact drutuherbalcure @ gmail . com. I showed it to brown who confirmed it was Dr Utu contact. I contacted him immediately and he also prepared and sent me herbal herpes meds through DHL. Right after getting this traditional meds I followed the prescription cautiously and withing days I started noticing rapid change and I know within me it's the cure. I used it for up to two weeks and when my test result was out not only did this herbal meds cure me but boost my immune and I feel real and free. Dr Utu African Traditional meds have successfully cured Herpes, Warts, HIV, Cancers, Kidney Stone, Asthma, most importantly this traditional meds boost immune and have no after effect.
for other general statements see Smith TJ, Hillner BE (May 2011). "Bending the cost curve in cancer care". The New England Journal of Medicine. 364 (21): 2060–5. doi:10.1056/NEJMsb1013826. PMC 4042405. PMID 21612477. and Peppercorn JM, Smith TJ, Helft PR, Debono DJ, Berry SR, Wollins DS, Hayes DM, Von Roenn JH, Schnipper LE (February 2011). "American society of clinical oncology statement: toward individualized care for patients with advanced cancer". Journal of Clinical Oncology. 29 (6): 755–60. doi:10.1200/JCO.2010.33.1744. PMID 21263086.
I purchased this product locally and as I walked back to my car, I was in so much pain in my feet and hands I wasnt sure I could make it back. I sat in my car and took a dropper full (1ml). As I was sitting there I could feel the inflammation in my hands disappear and the pain went away. My feet began to feel the effects next and the pain all but subsided. I hadnt been sleeping very good at night but last night I slept like a baby with NO pain. Why isnt this marketed as a product that is NON opiod and covered by insurance? Rheumatoid Arthritis is the most painful thing in the world but this helped me 100%. I almost cried last night I was so happy for a change! Thank you for making this product.
Individuals with arthritis can benefit from both physical and occupational therapy. In arthritis the joints become stiff and the range of movement can be limited. Physical therapy has been shown to significantly improve function, decrease pain, and delay need for surgical intervention in advanced cases.[43] Exercise prescribed by a physical therapist has been shown to be more effective than medications in treating osteoarthritis of the knee. Exercise often focuses on improving muscle strength, endurance and flexibility. In some cases, exercises may be designed to train balance. Occupational therapy can provide assistance with activities. Assistive technology is a tool used to aid a person's disability by reducing their physical barriers by improving the use of their damaged body part, typically after an amputation. Assistive technology devices can be customized to the patient or bought commercially.[44]

^ Ideguchi, Haruko; Ohno, Shigeru; Hattori, Hideaki; Senuma, Akiko; Ishigatsubo, Yoshiaki (2006). "Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs". Arthritis Research & Therapy. 8 (3): R76. doi:10.1186/ar1943. ISSN 1478-6354. PMC 1526642. PMID 16646983.
Vaccines have been developed that prevent infection by some carcinogenic viruses.[126] Human papillomavirus vaccine (Gardasil and Cervarix) decrease the risk of developing cervical cancer.[126] The hepatitis B vaccine prevents infection with hepatitis B virus and thus decreases the risk of liver cancer.[126] The administration of human papillomavirus and hepatitis B vaccinations is recommended when resources allow.[127]

Palliative therapy (medical care or treatment used to reduce disease symptoms but unable to cure the patient) utilizes the same treatments described above. It is done with the intent to extend and improve the quality of life of the terminally ill cancer patient. There are many other palliative treatments to reduce symptoms such as pain medications and antinausea medications.
A wide variety of solvents can be used for extraction, such as chloroform, dichloromethane, petroleum ether, naphtha, benzene, butane, methanol, ethanol, isopropanol, and olive oil.[2][9] Currently, resinoids are often obtained by extraction with supercritical carbon dioxide. The alcohols extract undesirable water-soluble substances such as chlorophyll and sugars (which can be removed later by washing with water). Non-polar solvents such as benzene, chloroform and petroleum ether will not extract the water-soluble constituents of marijuana or hashish while still producing hash oil. In general, non-polar cannabis extracts taste much better than polar extracts. Alkali washing further improves the odor and taste.
Osteoarthritis affects more than 3.8% of people while rheumatoid arthritis affects about 0.24% of people.[9] Gout affects about 1–2% of the Western population at some point in their lives.[10] In Australia about 15% of people are affected,[11] while in the United States more than 20% have a type of arthritis.[8][12] Overall the disease becomes more common with age.[8] Arthritis is a common reason that people miss work and can result in a decreased quality of life.[7] The term is derived from arthr- (meaning joint) and -itis (meaning inflammation).[13][14]

It is important to point out that most everyone has risk factors for cancer and is exposed to cancer-causing substances (for example, sunlight, secondary cigarette smoke, and X-rays) during their lifetime, but many individuals do not develop cancer. In addition, many people have the genes that are linked to cancer but do not develop it. Why? Although researchers may not be able give a satisfactory answer for every individual, it is clear that the higher the amount or level of cancer-causing materials a person is exposed to, the higher the chance the person will develop cancer. In addition, the people with genetic links to cancer may not develop it for similar reasons (lack of enough stimulus to make the genes function). In addition, some people may have a heightened immune response that controls or eliminates cells that are or potentially may become cancer cells. There is evidence that even certain dietary lifestyles may play a significant role in conjunction with the immune system to allow or prevent cancer cell survival. For these reasons, it is difficult to assign a specific cause of cancer to many individuals.
Glucosamine and chondroitin are substances that occur naturally in cartilage. Several studies have shown the benefit of oral glucosamine in osteoarthritis. In a systematic review, glucosamine was found to work as well or better than NSAIDS. (Although other studies have found it less effective.) Often glucosamine is used in combination with chondroitin, although studies are not clear as to whether there is added symptomatic improvement by adding chondroitin, there is suggestion that it may retard progression of the disease. These may be disease modifying agents, rather than just pain suppressing. Doses are 500 mg of glucosamine sulfate three times a day, with or without chondroitin sulfate 400 mg three times/day.  A minimum of a 6-week trial should be completed before symptomatic assessment is made.
Diabetic neuropathy (nerve damage). This makes it hard for your nerves to send messages to your brain and other parts of the body. You may lose feeling in parts of your body or have a painful, tingling, or burning feeling. Neuropathy most often affects the feet and legs. If you have neuropathy, you may not be able to feel a sore on your foot. The sore can become infected. In serious cases, the foot may have to be amputated (removed). People who have neuropathy may continue walking on a foot that has damaged joints or bones. This can lead to a condition called Charcot foot. Charcot foot causes swelling and instability in the injured foot. It can also cause the foot to become deformed. However, this problem can often be avoided. Check your feet every day. See your doctor immediately if you see swelling, redness, and feel warmth in your foot. These can be signs of Charcot foot. Your doctor should also check your feet frequently. Neuropathy also can cause erectile dysfunction in men and vaginal dryness in women.

Low blood sugar (hypoglycemia) is common in people with type 1 and type 2 DM. Most cases are mild and are not considered medical emergencies. Effects can range from feelings of unease, sweating, trembling, and increased appetite in mild cases to more serious effects such as confusion, changes in behavior such as aggressiveness, seizures, unconsciousness, and (rarely) permanent brain damage or death in severe cases.[23][24] Moderately low blood sugar may easily be mistaken for drunkenness;[25] rapid breathing and sweating, cold, pale skin are characteristic of low blood sugar but not definitive.[26] Mild to moderate cases are self-treated by eating or drinking something high in sugar. Severe cases can lead to unconsciousness and must be treated with intravenous glucose or injections with glucagon.[27]
Get into the extraction business: There is so much weed in Oregon (over a million pounds extra) that they want to export it to California. You do not hear the same story about weed extraction businesses. Instead, demand for cannabis oil vape cartridges continues to grow. In 2018, vape sales accounted for 22 percent of all dispensary sales in California, Colorado, Arizona and Oregon according to BDS Analytics. This makes vapes the second largest product category, behind flower.
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